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肝纤维化发生发展过程中肝温度的变化规律 |
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| 作者：佚名 文章来源：世界华人消化杂志 点击数： 更新时间：2004-11-1 15:19:51 |
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d by CCl4 changed with the time of the model made. In 2-wk model group, the infrared image temperature of right liver lobe was 28.6±1.1 °C, compared with 2-wk control group (P <0.05, t =-2.518). The temperature of 4-wk model group was 27.2±1.0 °C. In 6-wk model group, the temperature was 30.1±1.2 °C, compared with 6 wk control group (P <0.05, t =3.773). The temperature of 8-wk model group was 27.4±1.0 °C, compared with 8 wk control group (P <0.01, t =4.998). The histological changes of liver tissue were inflammation and hepatocytic degeneration and necrosis in 2-wk model group. There was a significant increase of extracellular matrix among the necrostic hepatocytes in 4-wk model group. In 6-wk model group liver tissue showed the numbers of necrostic hepatocytes increased significantly and the septa formed around central vein and portal area. In 8 wk model group, there were wide septa expansions from the portal area to the central venous and pseudo-nodular formation. Sirius red and immunohistochemical stains showed collagen types I, III and laminin expression in liver tissues increased gradually in 2-, 4-, 6-, 8- wk model group. Collagen type III was the main collagen in 2- and 4-wk model groups. Collagen type I was the main collagen in 6- and 8-wk model groups.
CONCLUSION: The liver temperature changes regularly with hepatic tissue pathology in course of rat hepatic fibrosis induced by CCl4.
Jiang T, Lv SW, Zhang SW, Li H, Pang YH, He WT. Alterations of liver temperature during hepatic fibrosis. Shijie Huaren Xiaohua Zazhi 2004;12(9):2111-2114
摘要
目的: 研究肝纤维化发生、发展过程中肝温度变化的规律.
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