Alterations of liver temperature during hepatic fibrosis
Tao Jiang, Shao-Wen Lv, Shi-Wu Zhang, Hong Li, Yi-Hui Pang, Wen-Tong He
Tao Jiang, Shao-Wen Lv, Hong Li, Yi-Hui Pang, Wen-Tong He, Department of Histology and Embryology, Medical College of Chinese People’s Armed Police Forces, Tianjin 300162, China
Shi-Wu Zhang, Department of Pathology, Medical College of Chinese People’s Armed Police Forces, Tianjin 300162, China
Supported by the Scientific Foundation of Chinese People’s Armed Police Forces, No.WKH 2002-2
Correspondence to: Tao Jiang, Department of Histology and Embryology, Medical College of Chinese People’s Armed Police Forces, Tianjin 300162, China. jt72@eyou.com
Received: 2004-06-24 Accepted: 2004-07-22
Abstract
AIM: To investigate the alterations of liver temperature during hepatic fibrosis in rats induced by CCl4.
METHODS: Liver fibrosis was induced in rats after administration of CCl4 twice a week for 8 weeks. The rat liver temperature in 2-, 4-, 6- and 8- wk models and control group rat was detected by computer-assisted infrared thermorgraphic technology. To observe the histological change, the liver tissue microarray in every group of animals was stained by hematoxylin and eosin. Sirius red stain and polarization microscopy method was used for I and III collagen expression. Immunohistochemistry was used for detection of laminin to outline the formation of basement membrane on hepatic sinusoids.
RESULTS: The average infrared images temperature of hepatic fibrosis in rats induce[1] [2] [3] [4] [5] [6] [7] [8] [9] [10] ... 下一页 >>
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